ITGB1 monoclonal antibody, clone MEM-101A (Biotin)
产品名称： ITGB1 monoclonal antibody, clone MEM-101A (Biotin)
英文名称： ITGB1 monoclonal antibody, clone MEM-101A (Biotin)
产品编号： MAB4547
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native ITGB1.
- Immunogen:
- Native purified ITGB1 from Raji Burkitt's lymphoma cell line.
- Host:
- Mouse
- Theoretical MW (kDa):
- 130
- Reactivity:
- Dog, Human, Pig
- Specificity:
- This antibody reacts with CD29 (integrin beta1 chain), a 130 KDa single chain type I glycoprotein expressed as a heterodimer (non-covalently associated with the integrin alpha subunits 1-6).
- Form:
- Liquid
- Conjugation:
- Biotin
- Concentration:
- 1 mg/mL
- Isotype:
- IgG1
- Storage Buffer:
- In PBS, pH 7.2 (15 mM sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane.
Simova S, Klima M, Cermak L, Sourkova V, Andera L.Apoptosis. 2008 Mar;13(3):423-36.
- 2.
- The role of beta1 integrin subfamily in anchorage-dependent apoptosis of breast carcinoma cells differing in multidrug resistance.
Morozevich GE, Kozlova NI, Preobrazhenskaya ME, Ushakova NA, Eltsov IA, Shtil AA, Berman AE.Biochemistry (Mosc). 2006 May;71(5):489-95.
- 3.
- Integrin alpha2beta1 regulates neutrophil recruitment and inflammatory activity in experimental colitis in mice.
Lundberg S, Lindholm J, Lindbom L, Hellstrom PM, Werr J.Inflamm Bowel Dis. 2006 Mar;12(3):172-7.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 3688
- Gene Name:
- ITGB1
- Gene Alias:
- CD29,FNRB,GPIIA,MDF2,MSK12,VLA-BETA,VLAB
- Gene Description:
- integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
- Omim ID:
- 135630
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000019420,OTTHUMP00000046253,OTTHUMP00000063731,OTTHUMP00000063732,OTTHUMP00000063733,fibronectin receptor beta subunit,integrin VLA-4 beta subunit,integrin beta 1
- Gene Pathway
- Arrhythmogenic right ventricular cardiomyopathy (ARVC)
- Axon guidance
- Cell adhesion molecules (CAMs)
- ECM-receptor interaction
- Focal adhesion
- Hypertrophic cardiomyopathy (HCM)
- Leukocyte transendothelial migration
- Pathogenic Escherichia coli infection - EHEC
- Pathways in cancer
- Regulation of actin cytoskeleton
- Small cell lung cancer